Abstract: The experiment was conducted with the objective of examining the effect of dietary high copper on the antioxydic function of kidney in ducklings. 360 one-day-old Tianfu meat ducklings were randomly divided into six groups and feed on diets as follows: Controls (Cu 8 mg·kg^-1) and high copper (Cu 100 mg·kg^-1，high copper groupⅠ；Cu 200 mg·kg^-1，high copper groupⅡ；Cu 400 mg·kg^-1，high copper group Ⅲ；Cu 600 mg·kg^-1，high copper group Ⅳ；Cu 800 mg·kg^-1，high copper groupⅤ) for six weeks. Compared with those of control group, the renal free fatty acids, malondialdehyde and hydroxy radical contents in high copper groups Ⅱ,Ⅲ, Ⅳ and Ⅴ, and the renal cuprozincsuperoxide dismutase(CuZn-SOD) in group Ⅴ were increased (P<0.01 or P<0.05). Also, the serum copper-protein (CP) activities in high copper groups Ⅲ, Ⅳ and Ⅴ and the serum CuZn-SOD activities in group V were lower (P<0.01 or P<0.05 ) than that in control group.The results showed that dietary copper exceed 200 mg·kg-1 impaired renal antioxydic function, and the renal function was finally depressed.