猪博卡病毒流行病学研究

畜牧兽医学报

猪博卡病毒流行病学研究

郝飞¹，汤德元^1*，李春燕¹，罗险峰²，张华²，马萍²，曾智勇^1*，洪尼宁²，刘霞²

（1. 贵州大学动物科学学院，贵阳 550025； 2. 贵州省动物疫病预防控制中心，贵阳 550008）

收稿日期:2012-04-05 出版日期:2012-10-25 发布日期:2012-10-25
通讯作者: 汤德元（1964-），男，教授，博士，硕士生导师，主要从事动物传染病病原分子生物学和中西兽医结合的教学科研工作，E-mail: tdyuan@163.com；曾智勇(1978-)，E-mail: as.zyeng@gzu.edu.cn
作者简介:郝飞（1988-），男，江苏如皋人，硕士研究生，主要从事动物传染病病原分子病毒学研究，E-mail: haofei19880812@163.com
基金资助:
贵州省2011年农业攻关项目资助［黔科合NY字（2011）3103号］；贵州省2010年农业科技攻关项目（黔科合NY字［2010］3042号）

Research on the Epidemiology of Porcine Bocavirus

HAO Fei¹, TANG De-yuan^1*, LI Chun-yan¹, LUO Xian-feng², ZHANG Hua², MA Ping², ZENG Zhi-yong^1*, HONG Ni-ning², LIU Xia²

(1.College of Animal Science, Guizhou University, Guiyang 550025, China; 2. Animal
Disease Prevention and Control Center in Guizhou Province, Guiyang 550008, China)

Received:2012-04-05 Online:2012-10-25 Published:2012-10-25

摘要/Abstract

摘要： 猪博卡病毒属于细小病毒科细小病毒亚科博卡病毒属单链线性DNA病毒，该病毒于2009年在瑞典发现。作为一种新型病毒，人们对其的研究仍处于初步探索阶段。本文从博卡病毒的由来、猪博卡病毒的发现、分类、基因组结构及流行病学等方面进行阐述，并根据GenBank收录的25条猪博卡病毒的部分基因和全基因序列，利用DNAStar分析软件，通过Jotun-Hein算法，分别从猪博卡病毒的NS、NP、VP以及全基因序列进行相似性临近排组分析，并建立了PBoV系统发育树。结果发现可将猪博卡病毒分为2个大支和若干遗传簇，但这些不同的遗传簇所包含的毒株在核苷酸序列上仍然存在着一定的差异。

Abstract: The Porcine Bocavirus was found in Sweden in 2009, which belongs to Parvovirus subfamily, Parvoviridae with singlestranded DNA. As a new kind of virus, the studies on Porcine Bocavirus is in the stage of preliminary exploration by humans. The paper has described the source, discovery, classification, genome and epidemiology of Porcine Bocavirus. According to the GenBank including partial and complete gene sequences of 25 Porcine Bocaviruses, we put analysis of arranging the group of homology on NS, NP, VP and complete gene sequences about PBoV with analysis software of DNAStar, arithmetic Jotun-Hein. And we established the PBoV system of Phylogenetic tree. The result revealed that the PBoV includes two large branches and many hereditary clusters. But there are some differences in the nucleotides sequences of different hereditary clusters containing strains.

中图分类号:

S852.659.2

郝飞，汤德元，李春燕，罗险峰，张华，马萍，曾智勇，洪尼宁，刘霞. 猪博卡病毒流行病学研究[J]. 畜牧兽医学报, doi: .

HAO Fei, TANG De-yuan, LI Chun-yan, LUO Xian-feng, ZHANG Hua, MA Ping, ZENG Zhi-yong, HONG Ni-ning, LIU Xia. Research on the Epidemiology of Porcine Bocavirus[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, doi: .

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