Abstract: Total 42 Northeast wild boars derived from Jilin、Heilongjiang and Liaoning provinces were investigated, and the genetic polymorphism of 7 structural sites in wild boars populations were detected using the techniques of PCR-SSCP and PCR-RFLP. Subsequently, the genetic co-adaptability of these genes was analyzed and the results showed that 5 of 7 sites (71.43%) are genetic disequilibrium, 6 of 18 sites combinations in different chromosomes are genetic disequilibrium for genetic coadaptability. All of 3 sites combinations in the same chromosome are genetic disequilibrium. Leptin-ECF18R, however, is in linkage disequilibrium. The cause of the genetic equilibrium in the sites combination of Leptin-ECF18R maybe the opposite effect between genetic coadaptability and linkage disequilibrium.