α-酮戊二酸的代谢机理、营养生理功能及其在养殖生产中的应用

doi:10.11843/j.issn.0366-6964.2020.05.004

摘要/Abstract

摘要： α-酮戊二酸（alpha-ketoglutarate，AKG）是谷氨酸和谷氨酰胺的前体物质，三羧酸循环（tricarboxylic acid cycle，TCA cycle）的重要中间物质，可作为谷氨酰胺最佳替代物。近年来，AKG因其良好的稳定性和独特的营养生理功能，受到研究者的广泛关注，并作为新型的功能性饲料添加剂应用于动物生产，对发展生态健康养殖业具有重要意义。本文就AKG的代谢机理、营养生理功能及其在养殖生产中的应用现状进行综述，旨在为AKG在养殖生产中的合理应用提供指导依据。

关键词: α-酮戊二酸, 代谢机理, 营养学功能, 动物生产应用

Abstract: α-ketoglutarate (AKG), an important intermediate in the cycle of tricarboxylic acid (TCA), is a precursor of glutamic acid and glutamine, also the best substitate of glutamine. As a new functional feed additive for animal production, AKG is receiving more and more attention recently due to its good stability and unique nutritional physiological functions, which will be of great significance for the development of ecological health breeding industry. This paper reviews the metabolic mechanism, nutritional physiological function and application of AKG in animal production, which would provide a direction for the further study and rational application of AKG.

Key words: α-ketoglutarate, metabolic mechanism, nutritional function, animal production application

中图分类号:

S816.7

李硕, 邹田德, 王自蕊, 游金明. α-酮戊二酸的代谢机理、营养生理功能及其在养殖生产中的应用[J]. 畜牧兽医学报, 2020, 51(5): 923-932.

LI Shuo, ZOU Tiande, WANG Zirui, YOU Jinming. The Metabolic Mechanism and Nutritional Physiological Function of α-ketoglutarate and Its Application in Livestock Production[J]. Acta Veterinaria et Zootechnica Sinica, 2020, 51(5): 923-932.

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