ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2008, Vol. 39 ›› Issue (12): 1661-1664.

• 遗传繁育 • Previous Articles     Next Articles

Association Analysis between DGAT1 Gene and Milk Production Traits in Chinese Holstein

JIA Jin1，2，MA Yan1，SUN Dong-xiao1，ZHANG Yi1，ZHANG Yuan1*   

  1. 1.College of Animal Science and Technology, China Agricultural University, Beijing 100193, China；2.Affiliated High School of InnerMongolian Normal University, Hohhot 010020, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2008-12-24 Published:2008-12-24

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Abstract: With PCR-RFLP technique, the polymorphism in the exon8 of DGAT1 gene were investigated in a population of 1 222 Chinese Holstein cows from 17 bull families. Three kinds of genotypes were found and the genotypic frequencies of KK, KA and AA were 0.143 2, 0.609 7 and 0.247 1, respectively-Using SAS (8.02) software with animal model, significant associations between the K232A mutation within exon8 of DGAT1 gene and three milk production traits were revealed. Duncan’s multiple-range test showed that the cows with AA genotype had higher 305day milk yield and protein yield than those with KA and KK genotypes (P<0.01), while had lower fat yield (P<0.01). The results suggested that DGAT1 gene has a great effect on milk production traits and could be a useful genetic marker in Chinese Holstein breeding.

Key words: Chinese Holstein, DGAT1, milk production traits, association analysis, PCR-RFLP