ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2007, Vol. 38 ›› Issue (5): 425-431.doi:

• 遗传繁育 • Previous Articles     Next Articles

Cloning, expression and bioinformatics analysis of miR-206 precursor in the pig

CHEN Jian-hai; WEI Wen-juan;XIAO Xiao; XIE Sheng-song;FENG Yang;ZHAO Shu-hong   

  1. Key Lab of Agricultural Animal Genetics,Breeding and Reproduction of Ministry of Education & Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, Huazhong Agricultural University, Huazhong Agriculture University
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-05-25 Published:2007-05-25

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Abstract: MiRNAs play important roles in skeletal muscle development. In this study, the porcine miR-206 precursor is cloned and sequenced from skeletal muscle through comparative genomics approach. The secondary structure was predicted. RT-PCR results indicated that the miR-206 precursor is expressed in most of the tissues and exhibited the highest expression level in skeletal muscle. Homology analysis revealed that pre-miR-206 is highly conserved among different species.