全基因组选择在猪育种中的应用

doi:10.11843/j.issn.0366-6964.2016.01.001

摘要/Abstract

摘要：

全基因组选择（Genomic selection，GS）是一种全基因组范围内的标记辅助选择方法。利用全基因组遗传标记信息对个体进行遗传评估，能够更加准确地早期预测估计育种值，降低近交系数，大大提高猪育种的遗传进展。随着猪全基因组测序的完成和猪60k SNP芯片的商业化，全基因组选择已经成为猪育种研究领域的新热点。本文综述了全基因组选择的分析方法、计算方法和影响因素，并阐述了全基因组选择在猪育种中的应用情况和发展趋势。

关键词: 全基因组选择, 猪, 育种, SNP芯片

Abstract:

Genomic selection (GS) is a maker-assisted selection method with the whole genome data.This approach could predict estimated breeding value with higher accuracy at early stage by analyzing the genetic markers covering the whole genome，and it also could decrease the inbreeding coefficient and improve the genetic progress substantially in swine breeding.With the achievement of swine genome sequencing and commercialization of PorineSNP60 Beadchip，the strategy of genomic selection has been becoming a new hot spot in swine breeding research area.In this review，we briefly summarized the analytical method，computing method and influence factors of GS，and we also elaborated the application situation and development tendency of GS in swine breeding.

Key words: genomic selection, swine, breeding, SNP chip

中图分类号:

S828
S813.3

王晨，秦珂，薛明，莫德林，陈瑶生，刘小红. 全基因组选择在猪育种中的应用[J]. 畜牧兽医学报, 2016, 47(1): 1-9.

WANG Chen，QIN Ke，XUE Ming，MO De-lin，CHEN Yao-sheng，LIU Xiao-hong. Application of Genomic Selection in Swine Breeding[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2016, 47(1): 1-9.

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