Abstract: The polymorphism of intron 4 in phospholipid transfer protein(PLTP) gene was detected by PCR-RFLP. A Hae Ⅲ RFLP was detected in intron 4 and the polymorphic locus is common in all detected groups. Associations between the founded Hae Ⅲ RFLP in intron 4 and birth weight, body weight at 45 days, body weight at 60 days, body weight at 4 months, body weight at 6 months, body height at 6 months, body length at 6 months and circumference at 6 months were tested by least square analysis. No significant difference between Hae Ⅲ RFLP and body weight at 45 days, body weight at 60 days, body weight at 6 months, body length at 6 months and circumference at 6 months were founded in this study.The results showed that the body weight at 4 months with aa genotype was higher than that with AA genotype(P<0.01), the body height at 6 months with aa genotype was higher than that with AA genotype(P<0.05), the birth weight with Aa genotype was higher than that with AA genotype(P<0.05). Therefore, it could be seen that porcine PLTP genotypes had significant influence on growth traits, this SNP might be considered as a potential genetic marker for selection.