哺乳动物原始卵泡的形成和发育及影响因素

doi:10.11843/j.issn.0366-6964.2015.01.003

摘要/Abstract

摘要：

原始卵泡形成和发育是成年动物卵巢发挥最优生产潜能的重要事件，在卵巢发育过程中起着至关重要的作用，然而卵巢发育相关研究中，人们更多地关注生长卵泡而忽视了原始卵泡。研究表明，不同物种的哺乳动物原始卵泡形成时间存在差异，影响原始卵泡形成和发育的主要因素有信号通路、生长因子、转录因子以及激素。本文就哺乳动物原始卵泡形成和发育以及影响因素作一综述。

关键词: 原始卵泡, 卵母细胞, 生殖细胞巢, 减数分裂, 信号通路

Abstract:

The formation and development of primordial follicle are the most important events in the ovary activation and exerting the optimum reproductive potency of an adult.Most researches about the follicular development were focused on the growing follicular，but not the primordial follicle.However，studies have shown that assembly timing of primordial follicle are differ between species.The signaling pathways，growth factor，transcription factors，hormone and other aspects collaborate to regulate the formation and development of primordial follicle.This paper will review the primordial follicle assembly，development and the influencing factors in the mammalian.

Key words: primordial follicle, oocyte, germ cell cyst, meiotic, signaling pathway

中图分类号:

S814

许蒙蒙，车龙，徐盛玉，吴德. 哺乳动物原始卵泡的形成和发育及影响因素[J]. 畜牧兽医学报, 2015, 46(1): 20-25.

XU Meng-meng，CHE Long，XU Sheng-yu，WU De. Influencing Factors and Assembly and Development of Primordial Follicle in the Mammalian[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2015, 46(1): 20-25.

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