Abstract: In 3×3 Latin square design, three wethers of Inner Mongolian White Cashmere (IMWC) goats (25~30 kg) with the same father, fitted with permanent cannulas at the proximal duodenum, and with carotid artery, mesenteric and portal venous catheters were used to investigate the effect of absorbable amino acid pattern in the small intestine, which were M, M90+C10 and M80+C20, on absorption and metabolism of amino acids in IMWC goats. The results showed absorbable amino acid pattern had significantly effect on MDV and PDV net flux of SAA, and Met net flux were significantly increased with increasing of the ratio of cashmere pattern in the target pattern (P＜0.05). MDV net flux of Cys was significantly greater than its disappearance in the small intestine (P＜0.05). Large BCAA amounts were extracted in the gastrointestinal tract, especially for Leu. It was suggested that absorbable amino acid pattern had significantly effect on amino acid metabolism in IMWC goats, and the ideal amino acid pattern should be between M90+C10 and M80+C20