日粮添加绿原酸和橙皮苷对断奶仔猪生长性能与肠道功能的影响

doi:10.11843/j.issn.0366-6964.2019.03.012

Abstract

Abstract:

The objective of this study was to investigate the effects of dietary chlorogenic acid (CHA) and hesperidin (HDN) on growth performance and intestinal function in weaned piglets. Forty Landrace×Yorkshire×Rongchang healthy castrated weaned male piglets ((28±2) d, (8.97±1.48) kg) were randomly divided into 4 groups (10 repeat per group, 1 piglet per repeat):control group (CON), Bacilli peptide group(BT), HDN group, CHA group. The experiment lasted for 33 d including 5 d adaptation period. The growth performance, biochemical indicators of plasma and liver, intestinal mucosa morphology, the expression of genes and proteins related to intestinal mucosa and colon microflora were determined. The results showed that:1) Compared with control group, the addition of CHA and HDN in basal diet of weaned piglets significantly increased the average daily gain, average daily feed intake, thymus index and small intestine length index (P<0.05), and significantly improved the total antioxidant capacity and the activity of total superoxide dismutase, catalase, glutathione reductase, glutathione peroxidase (P<0.05). 2) The height and integrity of jejunum villus of piglets in CHA, HDN and BT groups were better than those in CON group (P<0.05). 3) The β-defensins 2 concentration of piglets in CHA group were higher than those in CON group (P<0.05). The TNF-α mRNA level in jejunum villus of piglets in CHA group was higher than those in HDN and CON groups (P<0.05). The IL-8 mRNA level in jejunum villus of piglets in HDN group was higher than those in BT group (P<0.05). There was no significant difference in HSP₉₀ and TLR4 protein levels and TGF-β1 mRNA abundance among 4 groups (P>0.05). 4) CHA and HDN could maintain the diversity of the colonic microbiological flora of weaned piglets and protect the intestinal micro-ecological balance. The result indicate that dietary supplementation of chlorogenic acid and hesperidin increased average daily gain, average daily feed intake, jejunal mucosal villus height, and significantly reduced the ratio of feed to meat of weaned piglets. Chlorogenic acid plays an anti-bacterial role by promoting the expression of BD2 in intestinal epithelium and plays an anti-inflammatory role by enhancing TNF-α. Chlorogenic acid and hesperidin can maintain the diversity of intestinal microflora in weaned piglets.

CLC Number:

S816.79
S828

LAI Xing, CHEN Qingju, LU Changwen, MA Yajun, TANG Zhiru. The Effects of Dietary Chlorogenic Acid and Hesperidin on Growth Performance and Intestinal Function in Weaned Piglets[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2019, 50(3): 570-580.

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The Effects of Dietary Chlorogenic Acid and Hesperidin on Growth Performance and Intestinal Function in Weaned Piglets

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