ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2015, Vol. 46 ›› Issue (12): 2161-2168.doi: 10.11843/j.issn.0366-6964.2015.12.006

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Detecting Selection Signatures on X Chromosome of Debao Pony

LIU Xue-xue1,ADLIJIANG Halik1,DONG Kun-zhe1,WANG Yue-yue1,PAN Jian-fei2,PU Ya-bin1,HE Xiao-hong1,MA Yue-hui1,JIANG Lin1*   

  1. (1.Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100193,China;2.College of Animal Science and Technology,Gansu Agricultural University,Lanzhou 730070,China)
  • Received:2015-01-15 Online:2015-12-23 Published:2015-12-23

Abstract:

The study aimed to screen the selection signatures on X chromosome of Debao pony.The Illumina Equine 65K SNP BeadChip was used to perform a X-chromosomal scan on Debao pony,Yili horses and Mongolian horses and obtain 2 339 SNPs with high quality.The result showed that,based on these SNPs,we detected 2 regions(4.0-39.9 and 87.1-123.5 Mb) under strong selection on the X chromosome of Debao pony by 2 different methods,FST and XP-EHH.The 2 detected regions contained 64 outliers overlapping genes including BCORPHEXPNPLA4 and GPC3,which are related to the body size and the bone development.The results indicate that genes associated with growth on X chromosome are subject to strong artificial selection pressure during the breeding of the smallest Chinese pony.A few of them are not reported before and could be important candidate genes in future study.

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