[1] HOUDEBINE L M.Transgenic animal bioreactors[J].Transgenic Res,2000,9(4-5):305-320.
[2] MIGLIACCIO A R,BENGRA C,LING J H,et al.Stable and unstable transgene integration sites in the human genome:extinction of the Green Fluorescent Protein transgene in K562 cells[J].Gene,2000,256(1-2):197-214.
[3] YAMAUCHI Y,DOE B,AJDUK A,et al.Genomic DNA damage in mouse transgenesis[J].Biol Reprod,2007,77(5):803-812.
[4] KONG Q R,WU M L,HUAN Y J,et al.Transgene expression is associated with copy number and cytomegalovirus promoter methylation in transgenic pigs[J].PLoS One,2009,4(8):e6679.
[5] TACHIBANA M,SUGIMOTO K,FUKUSHIMA T,et al.Set domain-containing protein,G9a,is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3[J].J Biol Chem,2001,276(27):25309-25317.
[6] NAKAYAMA J I,RICE J C,STRAHL B D,et al.Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly[J].Science,2001,292(5514):110-113.
[7] BORTVIN A,EGGAN K,SKALETSKY H,et al.Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei[J].Development,2003,130(8):1673-1680.
[8] CHEN J K,LIU H,LIU J,et al.H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs[J].Nat Genet,2013,45(1):34-42.
[9] KUBICEK S,O'SULLIVAN R J,AUGUST E M,et al.Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase[J].Mol Cell,2007,25(3):473-481.
[10] SHI Y,DESPONTS C,DO J T,et al.Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds[J].Cell Stem Cell,2008,3(5):568-574.
[11] HUANG J J,ZHANG H Y,YAO J,et al.BIX-01294 increases pig cloning efficiency by improving epigenetic reprogramming of somatic cell nuclei[J].Reproduction,2016,151(1):39-49.
[12] HUANG Y F,JIANG X H,YU M,et al.Beneficial effects of diazepin-quinazolin-amine derivative (BIX-01294) on preimplantation development and molecular characteristics of cloned mouse embryos[J].Reprod Fertil Dev,2017,29(6):1260-1269.
[13] FU L,ZHANG J,YAN F X,et al.Abnormal histone H3K9 dimethylation but normal dimethyltransferase EHMT2 expression in cloned sheep embryos[J].Theriogenology,2012,78(9):1929-1938.
[14] VEDADI M,BARSYTE-LOVEJOY D,LIU F,et al.A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells[J].Nat Chem Biol,2011,7(8):566-574.
[15] WANG Y S,ZHANG Y J,MAO T C,et al.Treatment donor cells with UNC0638 modify the abnormal histone H3K9 dimethylation and gene expression in cloned goat embryos[J].Small Ruminant Res,2017,156:27-32.
[16] GARRICK D,FIERING S,MARTIN D I K,et al.Repeat-induced gene silencing in mammals[J].Nat Genet,1998,18(1):56-59.
[17] GAETANO C,CATALANO A,PALUMBO R,et al.Transcriptionally active drugs improve adenovirus vector performance in vitro and in vivo[J].Gene Ther,2000,7(19):1624-1630.
[18] LACHNER M,JENUWEIN T.The many faces of histone lysine methylation[J].Curr Opin Cell Biol,2002,14(3):286-298.
[19] LACHNER M,O'SULLIVAN R J,JENUWEIN T.An epigenetic road map for histone lysine methylation[J].J Cell Sci,2003,116(11):2117-2124.
[20] BANNISTER A J,ZEGERMAN P,PARTRIDGE J F,et al.Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain[J].Nature,2001,410(6824):120-124.
[21] NISHIOKA K,CHUIKOV S,SARMA K,et al.Set9,a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation[J].Genes Dev,2002,16(4):479-489.
[22] FELDMAN N,GERSON A,FANG J,et al.G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis[J].Nat Cell Biol,2006,8(2):188-194.
[23] EPSZTEJN-LITMAN S,FELDMAN N,ABU-REMAILEH M,et al.De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes[J].Nat Struct Mol Biol,2008,15(11):1176-1183.
[24] KANG J,KALANTRY S,RAO A.PGC7,H3K9me2 and Tet3:regulators of DNA methylation in zygotes[J].Cell Res,2013,23(1):6-9.
[25] PARK K E,JOHNSON C M,CABOT R A.IVMBIX-01294,an inhibitor of the histone methyltransferase EHMT2,disrupts histone H3 lysine 9(H3K9) dimethylation in the cleavage-stage porcine embryo[J].Reprod Fertil Dev,2012,24(6):813-821.
[26] FU L,YAN F X,AN X R,et al.Effects of the histone methyltransferase inhibitor UNC0638 on histone H3K9 dimethylation of cultured ovine somatic cells and development of resulting early cloned embryos[J].Reprod Domest Anim,2014,49(2):e21-e25.
[27] 黄波.TSA浓度及处理时间对猪体细胞核移植胚胎体外发育及转基因eGFP表达的影响[D].哈尔滨:东北农业大学,2010.
HUANG B.Effect of TSA concentration and treatment period on the in vitro development and transgene eGFP expression of pig somatic cell nuclear transfer embryos[D].Harbin:Northeast Agricultural University,2010.(in Chinese)
[28] 张一军.UNCO638和2-PCPA对山羊早期克隆胚胎组蛋白甲基化的影响[D].杨凌:西北农林科技大学,2014.
ZHANG Y J.Effect of UNC0638 and 2-PCPA on histone modifications in early goat cloned embryos[D].Yangling:Northwest A&F University,2014.(in Chinese) |