ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2019, Vol. 50 ›› Issue (4): 721-726.doi: 10.11843/j.issn.0366-6964.2019.04.005

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Association of Genetic Resistance Loci to Subgroup A Avian Leukosis Virus with Important Economic Traits in Broilers

GAN Shiyi, WANG Jie, LUO Chenglong, QU Hao, SHU Dingming*   

  1. Guangdong Key Laboratory of Animal Breeding and Nutrition, State Key Laboratory of Livestock and Poultry Breeding, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China
  • Received:2018-09-25 Online:2019-04-23 Published:2019-04-23

Abstract:

To investigate the association of genetic resistance loci to subgroup A avian leukosis virus(ALV) with important economic traits, the genetic variations within resistance loci of tva gene were screened in an F2 resource population of broilers, which contained 788 healthy chicken. Production-related traits such as body weight, breast muscle weight, leg muscle weight on 6, 8, 10, 12 weeks and slaughter weight were measured, separately, and their association with genetic resistance loci to subgroup A avian leukosis virus was analyzed. Three variants (tvar3, tvar5 and tvar6, named tvamut502-516) were discovered in the F2 population. Association analysis revealed that the tvamut502-516 was significantly associated with abdominal fat weight (AFW) and abdominal fat rate (AFR) (P<0.05), but not significantly associated with growth, feed efficiency and other carcass traits (P>0.05). These results indicate that the mutation of genetic resistance loci to subgroup A avian leukosis virus can significantly decrease the AFW and AFR of chicken, and had no unfavorable effect on growth, feed efficiency and other carcass traits, therefore, these loci can balance the ALV-A resistance and growth development, can be applied in subgroup A ALV resistant breeding of broilers.

Key words: broilers, tva receptor gene, genetic resistance, subgroup A avian leukosis virus, economic traits

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